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Major Achievements

Tea seed meal can be included up to 2.9% of the diet without any adverse effect on health of adult Gaddi goats.
Tea seed saponins at the level of 600 ppm may be supplemented in broiler ration for improving nitrogen and mineral retention and to reduce triglyceride and LDL cholesterol levels.
Optimization of ensiling combination ratio of agrowastes viz., apple pomace, spent mushroom compost and wheat straw to develop agrowaste-based feed technology.
Overnight digested pasteurized (at 72°C) milk whey of indigenous cattle was found to strongly inhibit the enteropathogenic Escherichia coli.
Gastric hydrolysate of Gaddi goat boiled milk casein showed highest antagonism (zone of inhibition being 21 mm) against Staphylococcus aureus.
Antihypertensive activity in overnight intestinal digested 72°C pasteurized casein of indigenous cattle (71.99%) was higher in comparison to Gaddi goat (62.98%).
Total phenol content (TPC) and Ferric Reducing Antioxidant Potential (FRAP) values were increased in indigenous and Jersey cross-bred cattle boiled milks.
Gaddi goat boiled milk whey proteins (β-lactoglobulin, α-lactalbumin), appeared to be resistant to both gastric and intestinal digestion under in vitro conditions.
A total of 376 rumen bacteria, and five fungal isolates capable of degrading hydrolysable tannins (HTs) were obtained from the rumen of migratory Gaddi goats. A total of 106 bacteria could degrade HTs extracted from native plants namely Quercus leucotrichophora, Terminalia arjuna, T. chebula, T. bellerica, Pyrus pashia, Mangifera indica and Syzygium cumini.
Impact and implications of rumen microbial fermentation of added phytochemicals in ensiled forages has been deciphered.
Treatment with allyl isothiocyanate (0.008% v/v) reduced inflammatory and pre-neoplastic changes in the urinary bladder of fern-fed (Dryopteris nigropalaceae, 20% w/w, 360 dpf) Guinea pigs.
The concentration of ptaquiloside and pterosin B in some of the ferns collected from Kullu and Chamba regions of Himachal Pradesh ranged from 0 to 358.6 ± 70.5 mg/g and 0 to 652.4 ± 50.0 mg/g, respectively.
Profiling of lantadenes content in the leaves of Lantana camara collected from 10 districts of Himachal Pradesh revealed highest concentration of lantadenes in district Mandi (71.72%) and lowest in Bilaspur (33.41%).
Asparagus adscendens fruit saponins-enriched fraction (100 μg) exhibited significantly enhanced specific antibody and cellular immune response against ovalbumin in mice, thereby suggesting adjuvant activity.

Effect of in vitro digestion on indigenous cattle milk proteins. Lanes 1, 2, 3- Raw milk undigested, pepsin digested, trypsin-pancreatin digested (overnight); Lanes 4, 5, 6- 63°C Pasteurized whole milk undigested, pepsin digested, trypsin-pancreatin digested (overnight); Lane 7- HiMedia marker; Lanes 8, 9, 10- 72°C Pasteurized whole milk undigested, pepsin digested, trypsin-pancreatin digested (overnight); Lanes 11, 12, 13- Boiled whole milk undigested, pepsin digested, trypsin-pancreatin digested (overnight).

Urinary bladder (360 dpf Dryopteris nigropalaceae dried fern powder, 20% w/w) showing dysplasia and mitotic figure in urothelium of a Guinea pig. HEx400.