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Major Achievements

  • Genetically modified S19 strain of Brucella abortus (S19Δper) as vaccine candidate.
  • Whole genome sequencing of Brucella abortus S19Δper, Pasturella multocida (bovine and duck origin) and multidrug resistant E. coli isolates.
  • Recombinant antigen based latex agglutination test for sero-diagnosis of leptospirosis.
  • Freedom status from Contagious Bovine Pleuropneumonia infection in cattle & buffalo obtained from OIE.
  • Tube based LAMP for detection of multiple pathogens - Brucella, Leptospira and BoHV1.
  • Sero diagnostic test for Caprine Pleuropneumonia in goats
  • Indirect ELISA for detection of antibodies against P. multocida.
  • Recombinant cocktail comprising rOmpA and rOmpC was evaluated against Salmonella challenge.
  • Chimeric DNA vaccine construct and recombinant fusion protein generated against bovine brucellosis as candidate antigens.
  • Immunoreactive cell-wall associated proteins of Clostridium chauvoei were identified.
  • Repository of bacterial and fungal cultures.
  • Analysis of about 1000 clinical samples of neonates revealed E. coli, Group A Rota virus, picobirna virus, Eimeria spp. and Clostridium perfringens to be the major pathogens
  • Multi drug resistant E. coli recorded among neonates.
  • Generation of aroA mutant of Pasteurella multocida P52, cctA gene mutant of Clostridium chauvoei and ΔrfbD of B. abortus.
  • Multiplex PCR for detection of Mycoplasma bovis, M. bovigenitalium, M. leachii, M. arginini and M. mycoides subsp mycoides.
  • Real Time PCR for detection of M. bovis and M. bovigenitalium.
  • Molecular characterization of Indian isolated of Mycoplasma mycoides subsp. capri by MLST
  • Antibiogram profiling of Indian isolates of Mycoplasma species of caprine origin.
  • Evaluation of immuno-modulatory role of extra cellular vesicles of Mycoplasma mycoides subsp. capri and M. bovis in laboratory animal.
  • Several Salmonella serovars, namely Billa, Mons, Muenchen, Reinckandorf, Starrenbos, Uganda, Wein, S.I.17:d:1,2, S.1.17:d (Monophasic) were identified for the first time in India.
  • PCR assays using pncA and oxyR for species identification of Mycobacterium tuberculosis and M. bovis.
  • PCR assays using 26S rRNA and ITS-2 genes for identification of Malassezia and Candida.
  • Multiplex PCR for detection of Malassezia sp and Candida sp standardized
  • AMR studies of most common clinical fungi revealed high degree of resistance and existence of MDR strains.
  • Phylogenetic analysis of fungal isolates (Malassezia sp and Candida sp) shown close association between human and animal fungal strains.
  • Phylogenetic studies revealed sub clustering within the single Malassezia sp and candida species and genetic relatedness with other strains.
  • Multilocus sequence typing (MLST) of P. multocida, E. coli and C. perfringens
  • AMR studies of most common clinical fungi revealed high degree of resistance and existence of MDR strains.
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Coloured antigen for diagnosis of Caprine Pleuropneumonia
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Microscopic agglutination test for diagnosis of leptospirosis
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Latex agglutination test for diagnosis of leptospirosis