» About IVRI

Achievements

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IVRI Lab
IVRI Lab
IVRI Lab
IVRI Lab
IVRI Lab
IVRI Lab
IVRI Lab
IVRI Lab
IVRI Lab

The Institute with its long heritage and glorious scientific achievements has always enjoyed a certain prestige and tradition of its own. The Institute at its headquarters functions through 22 research divisions and 3 sections, 400 acres livestock and fodder production farms, feed technology unit, a modern computerised library, engineering section, medical hospital, etc. Besides the main campus, four regional stations at Kolkata, Palampur, Srinagar and Pune, and two full-fledged campuses at Mukteswar (Uttarakhand) and Bengaluru (Karnataka) are the other functional units of the Institute dedicated to livestock research and development. Further, the Institute is the seat of two Centres of Advanced Studies in Animal Nutrition, and Veterinary Physiology, many a Network projects and AICRPs.

Past Achievements

The Institute, the largest of its kind in whole of South-east Asia, is widely known for its impressive contributions to all aspects of livestock and poultry health, production technology and postgraduate education. The Institute is a pioneer not only in mission-oriented research, but also a foremost centre for postgraduate training and education. For many in the profession it is their Alma Mater.

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The Institute takes a legitimate pride in its contributions and distinguished services pro rata in achieving the national goals. With the richest animal resource in the world today, India is the largest milk producer and ranks fourth in egg production and eighth in broiler production in the world. These notable achievements became a reality due to direct impact on account of control of major diseases, particularly rinderpest and CBPP in cattle, African horse sickness in horses and Newcastle disease in poultry as a result of potent vaccines developed by IVRI. Some of the salient achievements are summarized below:

A. Animal Health

Vaccine/Prophylactics

  • Development of anti-sera against rinderpest (1899), anthrax (1902), and Haemorrhagic septicaemia (HS) (1905) in cattle
  • Development and production of Black quarter (BQ) vaccine (1906-08), polyvalent HS vaccine (1908), anthrax spore vaccine (1951), Contagious Caprine Pluero Pneumonia (CCPP) vaccine (2000)
  • Development of goat tissue vaccine (GTV) against rinderpest (1927), FMD vaccines including crystal violet tongue epithelium (1946-52), goat kidney cell culture (1964-65), saponin and oil adjuvant (1968-70) and BHK- 21 monolayer and cell suspension (1971-78) vaccines
  • Development of R2B vaccine against Ranikhet disease (1940), IBD (1999), thermostable IBD vaccine (2001) and an inactivated oil emulsified vaccine against inclusion body hepatitis-hydropericardium syndrome (IBH- HPS) (2000)
  • Development of an irradiated sheep lung worm vaccine (1973) and Theileria schizont culture vaccine for bovine tropical theileriosis (1979)
  • Development of therapeutics for surra (T. evansi infection) in horses and camels (1908-11)
  • Olinall®, a formula for treatment of chronic skin ailments commercialized (1997)
  • Development of drugs/formulations from indigenous medicinal plants for skin infections, ecto-and endoparasites and wounds (1990-96)
  • A post-milking herbal teat dip for prevention of bovine mastitis (2008)
  • Standardization of fermenter technology for large scale production of FMD vaccine in BHK-21 (clone 13) cells in suspension (1976-79)
  • Conferment of 100 per cent protection in challenged calves by a low volume (2 ml) saponified haemorrhagic septicaemia vaccine, up to 12 months post immunization (2004)
  • Conferment of 100 per cent protection in mares challenged with a virulent S. Abortus equi strain by defined deletion double mutant vaccine for Salmonella Abortus equi (2004)

Diagnostics

  • Development of ELISA technology for diagnosis of salmonellosis, brucellosis, listeriosis, theileriosis, babesiosis, trypanosomosis, fasciolosis, echinococcosis (1995-99), BVD, PPR (2003) and IBH-HPS (2000), IBD and NDV (2007)
  • Development of monoclonal antibodies against P. multocida (1994-95), FMD virus O, A, C and Asia-1 (1994-96), Bovine herpes virus-1 (1995-96), Salmonella Enteritidis (1996-97), Buffalo pox virus (1998-99), rinderpest virus and a MAb based competitive ELISA to distinguish rinderpest and PPR viruses (1997-99)
  • Development and release of a kit for diagnosis of bluetongue (1998), FMD (1998), and rinderpest (2001)
  • Development of Rose Bengal coloured antigen for serum agglutination test (1999-2000) and kit for diagnosis of caprine pleuropneumonia
  • Development of PCR assay and a non-isotopic gene probe for detection of Trypanosoma evansi (1998-2000)
  • Standardization of ELISA and PCR for the diagnosis of Mycoides clusters of Mycoplasma viz., Mycoides mycoides Subsp. capri, M. mycoides Subsp. mycoides Type LC, M. capricolum Subsp. capricolumn, M. capricolum, Subsp. capripneumoniae and Mycoplasma sp. bovine group 7 (1999)
  • PCR assays for chicken infectious anaemia (CIA) (2000), Theileria annulata and Babesia bigemina (2001), IBD, NDV, EDS-76, Avian Reovirus, duck plague (2001), fowl adenovirus-4 (2003), bovine picobirnavirus, and for detection of benzimidazole resistance in Haemonchus contortus (2011) and equine small strongyles (2015).
  • Development of real-time PCR assay for Capri poxviruses in sheep and goats (2008), avian influenza virus and pseudorabies (2006), pox viruses (Orf, buffalo pox), rotavirus (2010), Classical swine fever virus in pigs (2009)
  • Development of Dot-ELISA for quick diagnosis of PPR infection in small ruminants (2004) and Fasciola gigantica infection (2007)
  • Development of multiplex PCR for listeriosis and nested PCR for BDV, BVDV (type 1 & 2) and T. evansi (2006)
  • Recombinant diagnostic antigens viz., FMDV (P1) polyprotein, PPR (H protein), RD (HN protein), brucellosis L7/L12 ribosomal protein) and IBD (VP2) protein) were produced (2006)
  • A lateral flow rapid test and a DIVA-based multi-species indirect ELISA for FMD (2013)
  • Commercialization of IVRI crystoscope (2005)

Diagnostics

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IVRI Lab
  • Molecular characterization and differentiation of P. multocida strains, Salmonella serovars of veterinary and zoonotic significance using ribotyping, PCR and DNA fingerprinting techniques (1992-2000)
  • Detection of H5N1 subtype of influenza virus in poultry for the first time in the country. Four H9N2 and one H9N1 viruses were isolated (2006)
  • Border disease virus (BDV) isolated from Indian sheep (2009)
  • Porcine circovirus 2, the causative agent of PMWS, an emerging disease of pig, was first identified in the Indian swine population (2009)
  • Swine influenza (H1N1) pdm 2009 was isolated from sick pigs (2010)
  • Phylogenetically new strain of H5N1 (clade 2.3.2) was identified from 2011 outbreak in ducks of Tripura (2011)
  • Genetic characterization of Babesia gibsoni revealed circulation of several genetic variants in dog population of India.

Surgical interventions

  • Successful use of horn plates in the management of long bone fractures in animals (1986-90)
  • Design and fabrication of an external skeletal fixation device for stable fixation of metatarsal and radial fractures in large animals (1999)
  • Successful fixation of fractures in dogs with osteopenic bones by modified technique of interlocking nailing (2004)
  • Epoxy-pin external skeletal fixation technique has been developed for a variety of compound fractures of long bones in small animals (2007)
  • A novel design of bilateral external fixator for the management of long bone fractures in large animals (2007)
  • A cart for rehabilitation of dogs suffering from posterior paresis (2008)
  • Developed interlocking nails and designer locking plates for fixation of fractures in different long bones in cattle and buffaloes (2009-14)

B. LIVESTOCK IMPROVEMENT / MANAGEMENT

IVRI Lab
  • Introduction of Japanese quail (Coturnix coturnix japonica) as an alternate to poultry for the first time in India (1974)
  • Development and release of a high yielding broiler (B77) of poultry (1977)
  • Development of urea-molasses liquid feed and urea-molasses mineral liquid supplement for efficient utilization of low grade straws by ruminants (1980-85)
  • Breeding new strains of high yielding cattle (3000-3500 kg of milk / 300 days of lactation) (1986-97)
  • Utilization of agro-industrial by-products like mahua cake, neem seed cake, sal seed meal, tomato pumace, etc. and unconventional feed stuffs as livestock feed (1990-95)
  • Development of a promising diet for growing pigs and feeding standards for buffaloes, rabbits and guinea fowls (1990-95)
  • The feeding of lactics (lactic acid bacteria) to pre-ruminant calves and yeast to adult ruminants improved animal productivity (1995-2000)
  • Design and fabrication of a simple field diagnostic tool ‘Crystoscope’ for assessing the optimum insemination time in cows and buffaloes (1999)
  • A pregnancy-specific marker protein of placental origin in serum of pregnant goats was characterized (2001)
  • Evaluation of sugarcane bagasse pith as a sole roughage during scarcity (2002)
  • Technology development for utilization of karanj cake, urea-ammoniated sugar cane bagasse and kitchen waste as livestock feed (2003)
  • Genotyping of various genes namely, IGF BP-3, IL-2, IL-10, NRAMP-1, DRB-3 and ITGB-2 genes that affect growth/ production performance and/or disease resistance was done in buffaloes and goats (2003)
  • Development of a lifting device for sick and convalescent large animals (2003)
  • Restoration of fertility in endometric cows by autologus plasma and ketocytes (2004)
  • Development of a tractor operated animal carrier (2004)
  • Development of cross-bred cattle strain ‘Vrindavani’ (2006)
  • Transgenic mesenchymal stem cells expressing green fluorescence protein was produced (2011)
  • A new garbage processing indigenous earthworm strain designated as “Jai Perionyx Gopal” was ceylenesis developed having high fecundity, heat tolerance and inhabiting ability on animal and farm waste (2011-12)
  • A whole-genome (Black Bengal breed, male, 2.8 GB, 30X) has been sequenced and assembled (2012-13)
  • Knockdown of myostatin gene using siRNA and shRNA in caprine fetal myoblast was demonstrated (2012-13)
  • Metagenomic analysis of rumen microbiota indicated that cattle and buffalo are similar in their rumen microbial community structure and ability of fibre degradation (2013-14)
  • A canine-origin probiotic improved fiber digestibility, antioxidant status, cell mediated immunity and favourably altered the hind gut fermentation in dogs. It was found superior to the dairy-origin probiotic (2014-15)

C. LIVESTOCK PRODUCTS TECHNOLOGY

  • Development of technologies for pickle and emulsion based value added products such as sausages, patties, nuggets and balls from meat of spent hens, mutton, pork, rabbit and buffalo meat (1980-2000).
  • Development of processing technologies and economic formulations for emulsion based and restructured meat products by use of vegetables, eggs and byproducts in chicken, pork, mutton and buffalo meat products (2000-2010).
  • Methods for production of enrobed chunks and meat products from spent hen, mutton, pork and buffalo meat (2004-2008).
  • Formulations for functional meat products having low salt, low fat, medium fibre contents (2008-2012).
  • Shelf stable meat snacks and variety meat products such as chips, slices, curls, rings, cubes and meat spread (2008-2013).
  • Identification of optimum post slaughter handling conditions and tenderization techniques to produce tender and juicier indigenous meat curries and meat products (2005-2010).
  • Development of indicator sensors and on- package sticker type time temperature indicators for monitoring meat quality and safety during storage conditions (2013-2016).
  • Formulation and processing conditions for preparation of variety of ready-to-eat/cook milk based products such as ‘Milk chips’, ‘Milk nimki’ ‘Milk rings’ and ‘Functional milk slices’ (2010-2015).
  • Development of sensitive and rapid species specific PCR assays for identification of species origin in meat and meat products (2008-2015).
  • Development of blend of Essential oils for improving shelf life and safety of meat products during storage at refrigerated temperature (2012-2016).
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IVRI Lab
IVRI Lab