Public Health Division

Major Achievements

  • Discovered a new and potent Brucella phage – Izatnagar (Iz) phage Gr 6.
Diagnostic technologies generated
  • Developed lateral flow assay, LAT, IgG and IgM ELISA for serodiagnosis of JE in pigs
  • Developed LAT for differentiating typical/atypical EAEC
  • Peptide-based (com1 and Ybgf and DnaK) LAT for serodiagnosis of Q fever
  • Modified Agglutination Test (MAT) for sero-diagnosis of toxoplasmosis in man and animals
  • LAT for detection of L. monocytogenes in enriched food samples as well as sero-diagnosis of listeriosis
  • Developed indirect ELISA for listeriosis using synthetic peptides (LLO-1 & LLO-2)
  • Developed com1 gene-based LAMP for detection of Coxiella burnetti
  • Developed IgG ELISA for serodiagnosis of JE in equines
  • Improvised enrichment broths/media for isolation of Salmonella spp. Listeria spp., Aeromonas spp.and Campylobacter spp.
Diagnostic assays standardized
  • PCR protocols for Salmonella, Aeromonas, Listeria, Brucella, Campylobacter, S. aureus, Arcobacter and diarrhoeagenic Escherichia coli pathotypes.
  • Rapid 16S rRNA RFLP approach for identification of eight enteric bacterial pathogens at genus level
  • LAMP test for Arcobacter butzleri and Salmonella spp.
  • RT-PCR for human and bovine rotavirus & JE virus
  • RT-LAMP/Real Time RT- PCR targeting NS1 gene for JE virus
  • Trans-PCR/Com1/ Real Time PCR for Coxiella burnetii
  • Immunoassays (FAT/ELISA/slide agglutination test) for Salmonella, Aeromonas & Listeria spp.
Findings documented
  • Ameliorative effect of Curd and Arjuna feeding on atherosclerosis lesions in lab animals
  • Genotyping & partial sequencing of rotavirus revealed presence of reassortant & uncommon strains
  • Predominance of Enteroaggregative E. coli from diarrhoeal cases of human infants and young animals
  • Campylobacter in biofilms exhibited many fold resistance against antibiotics than planktonic cells
  • Antimicrobial effect of probiotics (LAB) reported against multi-drug resistant-EAEC
  • Antimicrobial resistance genes detected in S. aureus, E. coli, Salmonella & Campylobacter spp.
Patents filed
  • Recombinant NS1 protein based indirect IgG ELISA for sero-surveillance of Japanese Encephalitis, and kit thereof’. Application No. 201611024016. Published on 16.02.2018
  • A chitosan based biopreservative mix for buffalo meat mince at 5±1°C. Application No. 2144/DEL/2007

This is the official website of ICAR-Indian Veterinary Research Institute (ICAR-IVRI), Izatnagar, an institute under Indian Council of Agricultural Research (ICAR), Deparment of Agricultural Research & Education (DARE), Ministry of Agriculture and Farmers Welfare, Government of India.

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