Major Achievements

  • Genetically modified S19 strain of Brucella abortus (S19Δper) as vaccine candidate.
  • Whole genome sequencing of Brucella abortus S19Δper, Pasturella multocida (bovine and duck origin) and multidrug resistant E. coli isolates.
  • Recombinant antigen based latex agglutination test for sero-diagnosis of leptospirosis.
  • Freedom status from Contagious Bovine Pleuropneumonia infection in cattle & buffalo obtained from OIE.
  • Tube based LAMP for detection of multiple pathogens - Brucella, Leptospira and BoHV1.
  • Sero diagnostic test for Caprine Pleuropneumonia in goats
  • Indirect ELISA for detection of antibodies against P. multocida.
  • Recombinant cocktail comprising rOmpA and rOmpC was evaluated against Salmonella challenge.
  • Chimeric DNA vaccine construct and recombinant fusion protein generated against bovine brucellosis as candidate antigens.
  • Immunoreactive cell-wall associated proteins of Clostridium chauvoei were identified.
  • Repository of bacterial and fungal cultures.
  • Analysis of about 1000 clinical samples of neonates revealed E. coli, Group A Rota virus, picobirna virus, Eimeria spp. and Clostridium perfringens to be the major pathogens
  • Multi drug resistant E. coli recorded among neonates.
  • Generation of aroA mutant of Pasteurella multocida P52, cctA gene mutant of Clostridium chauvoei and ΔrfbD of B. abortus.
  • Multiplex PCR for detection of Mycoplasma bovis, M. bovigenitalium, M. leachii, M. arginini and M. mycoides subsp mycoides.
  • Real Time PCR for detection of M. bovis and M. bovigenitalium.
  • Molecular characterization of Indian isolated of Mycoplasma mycoides subsp. capri by MLST
  • Antibiogram profiling of Indian isolates of Mycoplasma species of caprine origin.
  • Evaluation of immuno-modulatory role of extra cellular vesicles of Mycoplasma mycoides subsp. capri and M. bovis in laboratory animal.
  • Several Salmonella serovars, namely Billa, Mons, Muenchen, Reinckandorf, Starrenbos, Uganda, Wein, S.I.17:d:1,2, S.1.17:d (Monophasic) were identified for the first time in India.
  • PCR assays using pncA and oxyR for species identification of Mycobacterium tuberculosis and M. bovis.
  • PCR assays using 26S rRNA and ITS-2 genes for identification of Malassezia and Candida.
  • Multiplex PCR for detection of Malassezia sp and Candida sp standardized
  • AMR studies of most common clinical fungi revealed high degree of resistance and existence of MDR strains.
  • Phylogenetic analysis of fungal isolates (Malassezia sp and Candida sp) shown close association between human and animal fungal strains.
  • Phylogenetic studies revealed sub clustering within the single Malassezia sp and candida species and genetic relatedness with other strains.
  • Multilocus sequence typing (MLST) of P. multocida, E. coli and C. perfringens
  • AMR studies of most common clinical fungi revealed high degree of resistance and existence of MDR strains.
Coloured antigen for diagnosis of Caprine Pleuropneumonia
Microscopic agglutination test for diagnosis of leptospirosis
Latex agglutination test for diagnosis of leptospirosis